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The random escapades of Stan Smith, an extreme right wing CIA agent dealing with family life and keeping America safe, all in the most absurd way possible.
Best known for his animated hits American Dad! and Family Guy, MacFarlane is also a successful actor and producer of live action comedies.
The best thing about having an animated family for your sitcom? The teenage child-star never develops a drug problem and mysteriously disappears for two seasons. Cartoons only do what you draw them to do.
These adult friendly cartoons are more appropriate for Friday nights than Saturday mornings; featuring everything from erratic secret agents to alcoholic scientists, and unhygienic fry-cooks.
The Fox Network's "animation domination" began in December 1989, when The Simpsons premiered on Fox and the network has produced a series of animated series for adults ever since.
"Best" is of course subjective, but we incorporate audience ratings, popularity, and reviews to create this list of the greatest animated comedies for adults.
Superheroes have long been a staple of Saturday Morning kids cartoons, but these animated series targeted to adults subvert the genre (think a cartoon version of The Boys).