As sadomasochistic yakuza enforcer Kakihara searches for his missing boss he comes across Ichi, a repressed and psychotic killer who may be able to inflict levels of pain that Kakihara has only dreamed of.
A Nazi doctor who had a fetish for young boys feels guilt after torturing and murdering his latest victim, and throws himself off a roof. Some years later, the doctor, confined to an iron lung, accepts as his nurse a boy who secretly witnessed that killing.
Japanese troops round up Chinese and Russian prisoners of war and take them to a place called Squadron 731, where they are grotesquely tortured and experimented on to test new biological weapons.
Notorious Baltimore criminal and underground figure Divine goes up against Connie & Raymond Marble, a sleazy married couple who make a passionate attempt to humiliate her and seize her tabloid-given title as "The Filthiest Person Alive".
A New York University professor returns from a rescue mission to the Amazon rainforest with the footage shot by a lost team of documentarians who were making a film about the area's local cannibal tribes.
An aging porn star agrees to participate in an "art film" in order to make a clean break from the business, only to discover that he has been drafted into making a pedophilia and necrophilia themed snuff film.
Professional motorcycle racer Bud Clay heads from New Hampshire to California to race again. Along the way he meets various needy women who provide him with the cure to his own loneliness, but only a certain woman from his past will truly satisfy him.