In 18th century France, the Chevalier de Fronsac and his native American friend Mani are sent by the King to the Gevaudan province to investigate the killings of hundreds by a mysterious beast.
Selene, a beautiful vampire warrior, entrenched in a war between the vampire and werewolf races. Although she is aligned with the vampires, she falls in love with Michael, a human who is sought by werewolves for unknown reasons.
As his kingdom is being threatened by the Turks, young prince Vlad Tepes must become a monster feared by his own people in order to obtain the power needed to protect his own family, and the families of his kingdom.
Told from Igor's perspective, we see the troubled young assistant's dark origins, his redemptive friendship with the young medical student Viktor Von Frankenstein, and become eyewitnesses to the emergence of how Frankenstein became the man - and the legend - we know today.