A skeptical female clinical psychologist joins a priest-in-training and a blue-collar contractor as they investigate supposed miracles, demonic possession, and other extraordinary occurrences to see if there's a scientific explanation or if something truly supernatural is at work.
Paul investigates modern miracles for the Catholic Church. After he witnesses a true, supernatural miracle, only for his findings to be dismissed, Paul leaves behind the Church and is approached by Alva Keel to join his organization.
Daimon and Ana Helstrom are the son and daughter of a mysterious and powerful serial killer. The siblings have a complicated dynamic as they track down the terrorizing worst of humanity - each with their attitude and skills.